is the cytoskelton a target for pharmaceutical agents?
Yes it is. There are drugs that target the microtubule structure as well as those that deed on the actin based microfilament structure.
I deduce cytoskeletons are responsible for the formation and shape of cells.If by agents you be determined chemical agents, then almost certainly.If we're even aware its possible, I would say its be done or being researched as you read this.
I guess it would be, as the cytoskeleton is made of various proteis, mailnly actin. The problem you enjoy is specificity. As these proteins are in every cell of the body, likelihood are that a drug would be toxic.
Yes.
The cytoskeleton is intimately involved in the process of cell division and cell can't undergo mitosis in need changes within the structure and organisation of the microtubules of the cytoskeleton.
A number of drugs are known to affect the cytoskeleton, of which Taxol (paclitaxel) is probably the most widely used, but other anti-cancer drugs do equal. However, the effect may vary from drug to drug depending on the target cell type. For example, paclitaxel kill the cancer cells directly by inhibiting mundane cell division. But some newer drugs in clinical trials target tubulin contained by the endothelial cells inside layer blood vessels. This cause changes surrounded by the shape of the cells, making the blood vessel leaky and eventually, leads to collapse of the blood vessel in the cancer, adjectives them of nutrients and causing the tumour to die (at tiniest so they hope)
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