Is here any studies proving that the body can one and only use a abiding amount of headache drug?

i.e. Does taking 3 Advil any different from taking 6Is here any studies proving that the body can one and only use a abiding amount of headache drug?
Yes, it's called Toxicology
Taking too much tylonaol or similar meds can ineradicably destroy your liver.
Taking too much over long residence an cause headache (ironically)
Taking too mush Aspirin or similar meds can cause intestinal or stomach bleeding.